The formulas, plain-English
Cable resistance and signal loss
Resistance is ρ × (length × 2) ÷ cross-section. For copper at AWG 16 (1.31 mm²) over 5 m, that is 0.131 Ω round-trip. The voltage divider against speaker impedance gives the signal loss: dB = 20·log10(Z_load ÷ (Z_load + R_cable)).
Below −0.5 dB is generally inaudible; below −0.1 dB is bulletproof. Halve the cable length and you halve the resistance; double the gauge cross-section (3 AWG steps up) and you halve it too.
System damping factor
DF_system = Z_load ÷ (Z_amp_out + R_cable), where the amp's output impedance is its rated DF rolled back: Z_amp_out = Z_load ÷ DF_amp. Cable resistance is in series with the amp, so it directly degrades damping.
Damping factor governs how well the amplifier controls bass transients. Below 20 you lose grip on woofers; below 10 the bass becomes audibly loose. A high-DF amp (500+) gives you generous headroom against cable degradation.